Transcriptomic Response of Fusarium verticillioides to Variably Inhibitory Environmental Isolates of Streptomyces

Fusarium verticillioides is a mycotoxigenic fungus that threat to food and feed safety due its common infection of maize, global staple crop. A proposed strategy combat this the use biological control bacteria can inhibit reduce mycotoxin contamination. In study, effect multiple environmental isolates Streptomyces on F. was examined via transcriptome analysis. The strains ranged from inducing no visible response dramatic growth inhibition. Transcriptionally, responded proportionally strain inhibition with either little transcript changes thousands genes being differentially expressed. Expression in putative secondary metabolite gene clusters observed. Interestingly, involved fusaric acid cluster were suppressed by inhibitory Streptomyces. beta-lactamase encoding (FVEG_13172) found be highly induced specific deletion increased those strains. This study demonstrates does not have an all or nothing it encounters but rather measured proportional strength